Use of hyaluronan in gene therapy
AssigneeMeditech Research, Ltd.
InventorsEva A Turley, Samuel S Asculai
Life of this patent
Estimating the term…
Abstract
A method of treating a human suffering a disease or condition caused by a gene, cDNA or RNA-DNA oligonucleotide or RNA-DNA oligonucleotide hybrids or messenger RNA implicated in a disease or condition involving cells that express hyaluronic acid receptors is provided, the method comprising administering to such human, an effective dosage amount of a pharmaceutical composition comprising an effective amount of a form of hyaluronic acid selected from hyaluronic acid and/or a pharmaceutically acceptable salt thereof associated with/bound with an effective amount of anti-sense to the gene, cDNA or RNA-DNA oligonucleotide or RNA-DNA oligonucleotide hybrids or messenger RNA implicated in the disease or condition in a suitable pharmaceutically acceptable diluent.
Claims8
A method of enhancing uptake of a nucleic acid by a cell comprising contacting said cell with a composition comprising a nucleic acid associated with or bound to hyaluronic acid or a salt thereof.
Dependencies are inferred from the claim text.