Isolated nucleic acid molecule coding for tumor rejection antigen precursors MAGE-C1 and MAGE-C2 and uses thereof
AssigneeLudwig Institute for Cancer Research
InventorsSophie Lucas, Charles De Smet, Thierry Boon-Falleur
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Abstract
The invention relates to isolated nucleic acid molecules which code for antigens expressed by tumor cells which maybe recognized by cytotoxic T cells, leading to lysis of the tumor cells which express it. This invention also relates to vectors which are designed to encode the antigen expressed by tumor cells and also to cells transfected by the nucleic acid molecules or vectors which comprise the nucleic acid molecules. Various therapeutic and diagnostic uses arising out of the properties of the nucleic acid molecules and the antigens for which these code are also part of this invention.
Claims17
An isolated nucleic acid molecule comprising a nucleotide sequence set forth in SEQ ID NO:
- 18.
An isolated nucleic acid consisting of the nucleotide sequence set forth in SEQ ID NO:
- 18.
An isolated nucleic acid molecule comprising a nucleotide sequence set forth by nucleotides 330-1449 of SEQ ID NO:
- 18.
Dependencies are inferred from the claim text.