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US 6,475,764 B1Granted
Recombinant collagenase type I from clostridium histolyticum and its use for isolating cells and groups of cells
AssigneeRoche Diagnostics GmbH
InventorsHelmut Burtscher, Dorothee Ambrosius, Friederike Hesse
Life of this patent
Estimating the term…
Abstract
A polypeptide with the properties of collagenase class I from Clostridium histolyticum (CHC I) and the amino acid sequence SEQ ID NO:2 which is optionally N-terminally extended by one or several amino acids of the sequence SEQ ID NO:3 is advantageously suitable for the isolation of cells from mammalian tissue and human tissue.
Claims6
A polypeptide comprising the amino acid sequence SEQ ID NO:
- 2.
A polypeptide encoded by the sequence SEQ ID NO:
- 1, wherein said coding begins at nucleotide 1002, 1029, 1110, 1176 or 1254 of SEQ ID NO:
- 1.
Dependencies are inferred from the claim text.