Neutrophil chemotactic factor cloned cDNA and monoclonal antibodies thereto
AssigneeThe United States of America as represented by the Department of Health and Human Services
InventorsKouji Matsushima, Teizo Yoshimura, Edward J. Leonard, Joost Oppenheim, Ettore Appella, Stephen D. Showalter
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Abstract
An isolated, synthetic preparation of a novel neutrophil-specific chemotactic factor (NCF), monoclonal antibodies having specific binding affinity for NCF and a clone containing the complete cDNA coding sequence for NCF are disclosed.
Claims2
A kit for determining the level of NCF mRNA-present in a sample, comprising a container containing cDNA for NCF for performing assay to determine the level of mRNA for NCF in a biological sample.
A method for detecting the level of mRNA for NCF in a sample, comprising reacting said sample with cDNA and determining the occurrence of hybridization by any conventional technique, the presence of said cDNA-mRNA hybrids being indicative of the presence of mRNA for NCF in said sample.
Dependencies are inferred from the claim text.