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US 6,475,644 B1Granted
Radioactive coating solutions methods, and substrates
AssigneeRadiovascular Systems, L.L.C.
InventorsJanet M. Hampikian, Neal A. Scott
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AssigneeRadiovascular Systems, L.L.C.
InventorsJanet M. Hampikian, Neal A. Scott
Estimating the term…
Radioactive coating solutions and sol-gels, and corresponding methods for making a substrate radioactive by the application of the radioactive coating solutions and sol-gels thereto. The radioactive coating solution comprises at least one carrier metal and a radioisotope, which may be soluble or insoluble, and may further comprise a reducing agent. The radioactive sol-gel comprises at least one metal alkoxide and a radioisotope, which may be soluble or insoluble. Methods of making a substrate radioactive by coating with radioactive coating solutions or sol-gels are also disclosed, including electrodeposition, electroless deposition, spin coating and dip coating. In a particular embodiment, the radioactive coating formed by the method is a composite coating. Radioactive substrates are also disclosed, comprising a substrate and one or more radioactive coatings, which coatings may be the same or different. Suitable substrates include medical devices, such as catheters, stents, brachytherapy devices and guidewires, or components thereof Medical devices capable of generating asymmetric, or targeted, radiation fields are also disclosed.
A radioactive coating solution comprising (1) at least one dissolved carrier metal ion;
A method of coating a substrate with a radioactive material by electroless deposition comprising:
A method of coating a substrate with a radioactive material by electrodeposition comprising:
A radioactive coating solution comprising (1) at least one dissolved carrier metal ion and (2) a dissolved non-metal radioisotope.
A radioactive coating solution comprising (1) at least one dissolved carrier metal ion (2) dissolved 198Au , and (3) a reducing agent.
A method of coating a substrate with a radioactive material comprising:
A method of coating a substrate with a radioactive material, comprising contacting the substrate with a radioactive coating solution, under conditions sufficient to electrically deposit a radioactive coating onto the substrate, said coating solution comprising (1) at least one dissolved carrier metal and (2) a dissolved non-metal radioisotope, thereby forming a substrate comprising a radioactive coating.
A method of coating a substrate with a radioactive material, comprising contacting the substrate with a radioactive coating solution, under conditions sufficient to electrically deposit a radioactive coating onto the substrate, said coating solution comprising (1) at least one dissolved carrier metal and (2) dissolved 198Au, thereby forming a substrate comprising a radioactive coating.
A coated substrate comprising at least a first layer of a radioactive composite coating, which comprises a metal matrix and a radioactive phase dispersed therein, disposed on a substrate material, wherein said radioactive phase comprises an insoluble radioisotope or an insoluble compound of a radioisotope.
A radioactive delivery catheter comprising a component having at least a first layer of radioactive coating thereon, wherein said radioactive coating is formed from a radioactive coating solution comprising (1) at least one dissolved carrier metal ion;
A brachytherapy device comprising:
Dependencies are inferred from the claim text.