Process for increasing the stability of liposome suspensions that contain hydrophilic active ingredients
AssigneeSchering Corporation
InventorsAndreas Sachse, Georg Rossling, Jens Leike
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Abstract
A process for increasing the stability of liposome suspensions that contain hydrophilic active ingredients is described, which is characterized in that the active ingredient that is to be encapsulated in the liposomes is metered such that 5% to 95% by weight of the active ingredient is present in unencapsulated form.
Claims10
A method for diagnostic imaging of the liver of the patient, which comprises imaging for diagnostic purposes the liver of a patient who has been administered a liposome suspension containing a hydrophilic contrast medium wherein 30 to 70% by weight of the contrast medium is encapsulated in liposomes and the remaining contrast medium is not encapsulated in liposomes, such that the combined action of the unencapsulated contrast medium and the encapsulated contrast medium results in a long-lasting high density enhancement of the healthy liver tissue.
Dependencies are inferred from the claim text.