Sustained release compositions and the process for their preparation
AssigneeIpsen Pharma Biotech
InventorsMarc Pellet, Chantal Roume
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Abstract
The invention relates to compositions in the form of microcapsules or implants comprising a biodegradable polymeric or copolymeric excipient or a mixture of such excipients with an inherent viscosity of between 0.5 dl/g and 1.6 dl/g in CHCl3, and one active substance or a mixture of active substances, it being possible for said microcapsules or implants to release the active substance or mixture of active substances over a prolonged period of up to three months or more. These compositions may also comprise an active principle having a high specific surface area.
Claims9
A process for the preparation of a water-soluble substance of high specific surface area comprising:
- a lyophilization step in which the freezing step is carried out by spraying a dilute solution of the water-soluble substance onto a metal plate having a temperature below −50° C. to effect instantaneous freezing.
Dependencies are inferred from the claim text.