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AssigneeYoshitomi Pharmaceutical
InventorsTadaaki Inoue, Hideto Kodaira, Yoshihito Nawa, Ryoichiro Murashima, Shunichi Abe, Kazumasa Yokoyama
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Disclosed is an infusion preparation for nutrient supply use. It comprises a sugar, amino acids, electrolytes and a fat emulsion. It has an excellent shelf life without causing precipitation, denaturation and the like in spite of the simultaneous presence of these components. Also disclosed is a container filled with infusion liquids comprising a first and a second compartment separated from each other by a separation means, wherein an infusion liquid containing a fat emulsion and a sugar is included in the first compartment and another infusion liquid containing amino acids and electrolytes is included in the second compartment. Further disclosed are an infusion preparation comprising a fat emulsion and a sugar, and an infusion preparation comprising amino acids and electrolytes. An infusion preparation containing a sugar, amino acids, electrolytes and a fat emulsion can be obtained easily and aseptically upon use, by simply removing a separation means attached to the container and mixing the two infusion liquids.
An infusion preparation consisting essentially of an infusion liquid containing a fat emulsion, an anti-coloring agent selected from the group consisting of thioglycerol and dithiothreitol, and a reducing sugar, wherein said fat is contained in an amount of from 0.1 to 30% (w/v), said emulsifying agent used as an emulsifying agent for said fat emulsion is contained in an amount of from 0.01 to 10% (w/v) and said reducing sugar is contained in an amount of from 5 to 60% (w/v).
An infusion preparation comprising an infusion liquid containing a fat emulsion having a mean particle size of 0.17 μm or less and a sugar, which infusion liquid comprises a buffer agent selected from the group consisting of L-histidine and tris(hydroxymethyl)aminomethane, and mixtures thereof.
An infusion preparation comprising an infusion liquid containing a fat emulsion and a reducing sugar, wherein said fat is contained in an amount of from 0.1 to 30% (w/v), said emulsifying agent used as an emulsifying agent for said fat emulsion is contained in an amount of from 0.01 to 10% (w/v), said reducing sugar is contained in an amount of from 5 to 60% (w/v), and said fat emulsion has a mean particle size of 0.17 μm or less.
An infusion preparation consisting essentially of an infusion liquid containing a fat emulsion and a reducing sugar, wherein said fat is contained in an amount of from 0.1 to 30% (w/v), said emulsifying agent used as an emulsifying agent for said fat emulsion is contained in an amount of from 0.01 to 10% (w/v) and said reducing sugar is contained in an amount of from 5 to 60% (w/v), and wherein said fat emulsion has a mean particle size of 0.17 μm or less.
Dependencies are inferred from the claim text.