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AssigneeThe United States of America as represented by the United States National Aeronautics and Space Administration
InventorsWilliam T. Yost, John H. Cantrell
Estimating the term…
Changes in intracranial pressure can be measured dynamically and non-invasively by monitoring one or more cerebrospinal fluid pulsatile components. Pulsatile components such as systolic and diastolic blood pressures are partially transferred to the cerebrospinal fluid by way of blood vessels contained in the surrounding brain tissue and membrane. As intracranial pressure varies these cerebrospinal fluid pulsatile components also vary. Thus, intracranial pressure can be dynamically measured. Furthermore, use of acoustics allows the measurement to be completely non-invasive. In the preferred embodiment, phase comparison of a reflected acoustic signal to a reference signal using a constant frequency pulsed phase-locked-loop ultrasonic device allows the pulsatile components to be monitored. Calibrating the device by inducing a known change in intracranial pressure allows conversion to changes in intracranial pressure.
A method for non-invasive measurement of changes in intracranial pressure in a patient's head comprising the steps of:
An apparatus for non-invasive measurement of changes in intracranial pressure in a patient's head comprising:
A method for non-invasive measurement of changes in intracranial pressure in a patient's head comprising the steps of:
Dependencies are inferred from the claim text.