Valve for aerosol container
AssigneeSmithKline Beecham Corporation
InventorPeter Colin Weston Burt
Life of this patent
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Abstract
The invention is directed to a valve for an aerosol container for dispersing a suspension or solution of a medicament in a liquid propellant contained therein. The valve comprises a valve body defining an aperture, a seal mounted at the aperture, and a valve stem having a dispensing passage. The valve stem being slideably moveable through the seal such that in a first position the valve is closed to prevent the medicament and propellant from entering the dispensing passage. The valve stem also being such that in a second position the valve is open to allow the substance to be dispensed through the dispensing passage. The valve stem characterized in that it is constructed from a mouldable plastic and a mouldable lubricant.
Claims18
A drug product comprising:
- an aerosol container containing a drug formulation comprising one or more medicaments and one or more hydrofluoroalkane propellants attached to a valve;
- the valve comprising:
- a valve body defining a metering chamber,
- one or more gaskets suitable for slidingly engaging a valve stem;
- and,
- the valve stem constructed from a mouldable plastic and one or more fluorocarbon polymers, having a dispensing passage and in communication with the metering chamber,
- wherein the medicament is selected from the group consisting of terbutaline, fluticasone, beclomethasone, salmeterol, salbutamol, ipratropium, (−)-4-amino-3,5-dichloro-α-[[[6-[2-(2-pyridinyl)ethoxy]hexyl]amino]methyl]benzenemethanol, salts, esters and solvates thereof, and combinations thereof.
Dependencies are inferred from the claim text.