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US 6,472,536 B1Granted
2-(substituted-phenyl)amino-imidazoline derivatives
AssigneeSyntex (U.S.A.) Inc.
InventorsKeith Roger Bley, Robin Douglas Clark, Alam Jahangir, Bruce Andrew Kowalczyk, Francisco Javier Lopez-Tapia, Alexander Victor Muehldorf, Counde O'Yang, Thomas Weitao Sun
Life of this patent
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Abstract
This invention relates to IP receptor antagonists selected from the group of compounds represented by Formula I: where: R1 is a group represented by formula (A), (B) or (C); and other substituents as defined in the specification, and their pharmaceutically acceptable salts or crystal forms thereof; and pharmaceutical compositions containing them; and methods for their use as therapeutic agents.
Claims9
A compound selected from the group of compounds represented by Formula I:
- wherein
- R3 is selected from the group consisting of —(CH2)mOY wherein m is an integer from 0 to 3, and Y is selected from the group consisting of cycloalkyl and heterocyclyl, and
- R4 is selected from the group consisting of hydrogen and halogen;
- or
- pharmaceutically acceptable salts thereof.
2 more elements
Dependencies are inferred from the claim text.