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AssigneeJuridical Foundation: The Chemo-Seso-Therapeutic Research Institute
InventorsTakayuki Imamura, Hiroaki Maeda, Takeshi Fujiyasu, Yoshitaka Imagawa, Sachio Tokiyoshi
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A novel feline cytokine protein having the activity to enhance the cytotoxic activity of feline cytotoxic T lymphocytes, a DNA sequence coding for said protein, a recombinant DNA for expressing said protein, an expression vector comprising said recombinant DNA, a transformant which is transformed with said expression vector, a process for preparing said protein by culturing said transformant, and an antibody against said protein are provided. The novel feline cytokine protein of the present invention is a heterologous dimer comprising FLAF p35 and FLAF p40 and can be used for treating feline infectious diseases such as feline herpes virus type 1 (FHV-1) or feline calicivirus (FCV).
An isolated polypeptide comprising the amino acid sequence of SEQ ID NO:1.
An isolated polypeptide comprising the amino acid sequence of SEQ ID NO:1 with deletion, insertion or substitution at any one to several amino acid residues.
An isolated polypeptide comprising the amino acid sequence of SEQ ID NO:2.
An isolated polypeptide comprising the amino acid sequence of SEQ ID NO:2 with deletion, insertion or substitution at any one to several amino acid residues.
Dependencies are inferred from the claim text.