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US 6,472,508 B1Granted
Human tumor suppressor
AssigneeIncyte Genomics, Inc.
InventorsSam La Brie, Surya K. Goli
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AssigneeIncyte Genomics, Inc.
InventorsSam La Brie, Surya K. Goli
Estimating the term…
The present invention provides a novel human tumor suppressor (NHTS) and polynucleotides which identify and encode NHTS. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding NHTS and a method for producing NHTS. The invention also provides for agonists, antibodies, or antagonists specifically binding NHTS, and their use, in the prevention and treatment of diseases associated with expression of NHTS. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding NHTS for the treatment of diseases associated with the expression of NHTS. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding NHTS.
A substantially purified polypeptide comprising the amino acid sequence of SEQ ID NO:1.
Dependencies are inferred from the claim text.