Angiogenesis inhibition
AssigneeTrustees of Boston University
InventorSteven Moulton
Life of this patent
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Abstract
Angiogenesis is inhibited by the local administration of a pharmaceutical preparation formed from the reaction of hyaluronic acid, carboxymethylcellulose and a carbodiimide. The preparation, which can be in the form of a film or a gel, is advantageously applied directly to the site of a tumor, such as a cancerous tumor, used in conjunction with other chemotherapeutic techniques, or used to treat a chronic inflammatory condition, such as rheumatoid arthritis, endometriosis, arteriosclerosis, intimal hyperplasia, proliferative retinopathy, and the like.
Claims3
A method for inhibiting angiogenesis in a mammal comprising locally administering to the site of tumor formation in said mammal an angiogenesis inhibiting amount of a pharmaceutical preparation comprising the reaction product of hyaluronic acid, carboxymethylcellulose, and a carbodiimide.
Dependencies are inferred from the claim text.