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US 6,472,378 B2Granted
Compositions and methods for treatment of mitochondrial diseases
AssigneePro-Neuron, Inc.
InventorReid W. von Borstel
Life of this patent
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Abstract
Compounds, compositions, and methods are provided for treatment of disorders related to mitochondrial dysfunction. The methods comprise administering to a mammal a composition containing pyrimidine nucleotide precursors in amounts sufficient to treat symptoms resulting from mitochondrial respiratory chain deficiencies.
Claims8
A compound selected from the group consisting of 2′,3′,5′-tri-O-pyruvyluridine, 2′,3′-di-O-pyruvyluridine, 2′,5′di-O-pyruvyluridine, 3′,5′di-O-pyruvyluridine, 2′-O-pyruvyluridine, 3′-O-pyruvyluridine, and 5′-O-pyruvyluridine.
Dependencies are inferred from the claim text.