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US 6,472,178 B1Granted
Nucleic acids encoding a modified ciliary neurotrophic factor and method of making thereof
AssigneeRegeneron Pharmaceuticals, Inc.
InventorsJames P. Fandl, Neil E. Stahl, Stanley J. Wiegand
Life of this patent
Estimating the term…
Abstract
Modified ciliary neurotrophic factor, methods for production and methods of use, especially in the treatment of Huntington's disease, obesity, and gestational or adult onset diabetes.
Claims6
An isolated nucleic acid molecule encoding a modified human ciliary neurotrophic factor wherein the modifications consist of Cys17→Ala, Gln63→Arg and a deletion of the carboxy terminal 15 amino acid residues of human CNTF consisting of the sequence of SEQ ID NO:
- 1.
Dependencies are inferred from the claim text.