Use of an amphipathic compound for providing an adjuvant to a subunit vaccine
AssigneeAventis Pasteur Limited
InventorsAnne Darbouret, Florence Brunel, Jorge Ronco
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Abstract
The present invention provides a method of inducing an immune response to a subunit antigen in a non-responding subject by administering to the subject a composition comprising the subunit antigen and an amphipathic compound. A preferred antigen is a hepatitis B antigen, and a preferred amphipathic compound is DC-chol.
Claims13
A method of inducing an immune response to a subunit antigen in a non-responding subject, the method comprising administering to the subject a composition comprising the subunit antigen and an amphipathic compound.
A vaccine composition comprising a hepatitis B antigen and DC-chol.
Dependencies are inferred from the claim text.