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US 6,471,991 B2Granted
Soft chewable tablets having convexed shaped face surfaces
AssigneeMcNeil-PPC, Inc.
InventorsRonni L. Robinson, James R. Damon, James R. Mossop, Michael D. Palmer
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Abstract
The present invention relates to a compressed, chewable tablet containing at least one active ingredient, a water-disintegratable, compressible carbohydrate and a binder. These components are dry blended and compressed into convex-shaped tablet having a hardness of about 2 to about 11 kp/cm2 and friability less than 1%.
Claims32
A compressed, chewable tablet having opposed face surfaces, comprising:
- at least one active ingredient;
- a water-disintegratable, compressible carbohydrate;
- and
- a binder, said face surfaces having a convex shape and said tablet having an hardness of about 2 to about 11 kp/cm2.
1 more element
A compressed, chewable tablet having opposed major surfaces, comprising:
- at least one active ingredient coated with a taste masking coating;
- a water-disintegratable, compressible carbohydrate selected form the group consisting of mannitol, sorbitol, maltitol, dextrose, sucrose, xylitol, lactose, and mixtures thereof;
- and
- a binder selected form the group consisting of cellulose, cellulosic derivatives, polyvinyl pyrrolidone, starch, modified starch and mixtures thereof, said face surfaces having a convex shape and said tablet having a hardness of about 2 to about 11 kp/cm2 and a friability of less than about 1%.
1 more element
A process for preparing a compressed, chewable tablet, comprising the steps of:
- dry mixing at least one active ingredient, a water-disintegratable, compressible carbohydrate and a binder;
- and
- compressing the mixture into a tablet having convex shaped opposed face surfaces and a hardness of about 2 to about 11 kp/cm2.
Dependencies are inferred from the claim text.