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US 6,471,959 B1Granted
Human transferase
AssigneeIncyte Genomics, Inc.
InventorsPreeti Lal, Olga Bandman, Jennifer L. Hillman, Karl J. Guegler, Gina A. Gorgone, Neil C. Corley, Chandra Patterson
Life of this patent
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Abstract
The invention provides three human transferases (HUTRAN) and polynucleotides which identify and encode HUTRAN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of HUTRAN.
Claims7
An isolated polypeptide selected from the group consisting of:
- a) a polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO:1-3,
- b) a polypeptide comprising a naturally occurring amino acid sequence having at least 90% sequence identity to the amino acid sequence of SEQ ID NO:1, wherein said naturally occurring amino acid sequence has glutamine-phenylpyruvate aminotransferase activity,
- c) a polypeptide comprising a naturally occurring amino acid sequence having at least 90% sequence identity to the amino acid sequence of SEQ ID NO:2, wherein said naturally occurring amino acid sequence has kynurenine/α-aminoadipate aminotransferase activity, and
- d) a polypeptide comprising a naturally occurring amino acid sequence having at least 90% sequence identity to the amino acid sequence of SEQ ID NO:3, wherein said naturally occurring amino acid sequence has arginine methyltransferase activity.
1 more element
Dependencies are inferred from the claim text.