US 6,471,670 B1Granted

Fibrin sealant applicator system

OwnerKarl Enrenfels, Clifford L. Emmons +3inventors

InventorsKarl Enrenfels, Clifford L. Emmons, Chad Cimini, Csaba L. Reth, Tim Van Leeuwen

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Abstract

Fibrin sealant applicator systems are provided for dispensing a first and a second protein solution to form a biological adhesive which overcome the disadvantages of the prior art. The fibril sealant applicator system according to the present disclosure includes two piston-type sub-assemblies coupled to two vials storing a fibrinogen and a thrombin via a coupling unit. The piston-type sub-assemblies store sterilized water within reservoirs which are in fluid communication with the vials via the coupling unit. The water is forced into the vials to form a fibrinogen and a thrombin solution. The solutions are then drawn into the reservoirs and a Y-coupler is attached to the distal end of the piston-type sub-assemblies. The Y-coupler provides fluid communication between the reservoirs and a nozzle body for dispensing the solutions when distal pressure is created within the reservoirs to force the solutions towards the nozzle body.

Claims31

Dependent claims

An applicator system for dispensing a first solution and a second solution of a multicomponent biological adhesive, the applicator system comprising;

a piston-reservoir assembly having a reservoir sub-assembly coupled to a piston sub-assembly, said reservoir sub-assembly having two reservoirs and said piston sub-assembly having two pistons, each of said two reservoirs matingly engaging a corresponding one of said two pistons, said two pistons having fluid communication means for communicating fluid from said two reservoirs to a distal end of each of said two pistons;
and
a loading unit assembly configured for being coupled with said piston-reservoir assembly and at least two vials each storing at least one component of said multicomponent biological adhesive, said loading unit assembly having movable piercing means for moving towards said at least two vials and piercing a seal on each of said at least two vials, said loading unit assembly further having fluid communication means for communicating fluid from said distal end of each of said two pistons to an interior of each of said at least two vials by distally moving each of said two reservoirs toward each of said two pistons to decrease a volumetric capacity of each of said two reservoirs;
wherein each of said at least one component of said multicomponent biological adhesive is mixed with said fluid communicated from said distal end of each of said two pistons to said interior of each of said at least two vials to form said first and second solutions, said first and second solutions being communicated to a corresponding one of said two reservoirs via said fluid communication means of said loading unit assembly and said fluid communication means of said piston-reservoir assembly by proximally moving each of said two reservoirs away from each of said two pistons to increase said volumetric capacity of each of said two reservoirs, wherein said loading unit assembly being uncoupled from said piston-reservoir assembly for dispensing said first and second solutions of said multicomponent biological adhesive by compressing each of said two reservoirs toward each of said two pistons to decrease said volumetric capacity of each of said two reservoirs.

1 more element

A kit for dispensing a first solution and a second solution of a multicomponent biological adhesive, the kit comprising:

at least two piston assemblies each having a piston matingly engaging a reservoir storing a fluid therein, each of said pistons having fluid communication means for providing fluid communication between a corresponding one of said reservoirs and a distal end of said pistons for communicating said fluid stored within said reservoirs to said distal end of said pistons;
a loading unit assembly having a movable piercing shuttle, said movable piercing shuttle having a first end configured for coupling to said at least two piston assemblies and a second end configured for coupling to at least two vials each storing a component of said multicomponent biological adhesive, said loading unit assembly further having fluid communication means for communicating said fluid from said distal end of said pistons to an interior of each of said at least two vials by distally moving said reservoirs towards said pistons to mix said fluid with said components stored within said at least two vials to form said first and second solutions, said fluid communication means of said loading unit assembly further communicating said first and second solutions from said interior of each of said at least two vials to said reservoirs by proximally moving said reservoirs away from said pistons;
and
a dispensing unit assembly having at least two conduits each configured to align with a corresponding one of said fluid communication means of each of said pistons when coupling said dispensing unit assembly to said distal ends of said at least two piston assemblies, wherein said first and second solutions are dispensed by said dispensing unit assembly by distally moving said reservoirs towards said pistons.

1 more element

Dependencies are inferred from the claim text.

Facts

Application: 09/411,090Filed 4 Oct 1999 · us provisional application
Priority: 5 Oct 1998
Granted: 29 Oct 2002
Term ends: Not estimatedThe source records don’t support an estimate.

Classification5 codes

A61M 35/003
Devices for applying media, e.g. remedies, on the human body: portable hand-held applicators having means for dispensing or spreading integral media
A61B 17/00491
Surgical instruments, devices or methods: surgical glue applicators
A61B 2017/00495
Surgical glue applicators: for two-component glue
A61M
Devices for delivering substances into the body