Transmutable radiotherapy device
AssigneeRadioMed Corporation
InventorsPiran Sioshansi, Raymond J. Bricault
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Abstract
A general purpose radiotherapy device can be fabricated to net or near-net shape and then made radioactive in a single activation step. The device is made at least partially of a transmutable material which is transformable to a radioisotope-containing material upon activation by an accelerated beam of charged particles, such as protons, deuterons or alpha particles. The transmutable material is preferably rhodium and the radioisotope-containing material is preferably palladium-103.
Claims17
An interstitial radiotherapy device for in situ delivery of radiation to tumorous tissue at a treatment site in a patient, at least a portion of the device being made of rhodium which is transformable to palladium-103 upon activation by an accelerated beam of particles including protons having an energy of at least 4 MeV, wherein at least the rhodium portion of the device is formed to at least near-net shape, wherein the device is in the form of a wire.
A method of delivering radiation to tumorous tissue at a treatment site in a patient, comprising the steps of:
- a. providing an interstitial radiotherapy device in the form of a wire for in situ delivery of radiation to tumorous tissue at a treatment site in a patient, at least a portion of the device being made of rhodium which is transformable to palladium-103 upon activation by an accelerated beam of charged protons, wherein at least the rhodium portion of the device is formed to at least near-net shape;
- b. activating the device with a beam of charged protons having an energy of at least 4 MeV to form palladium-103;
- and
- c. placing the device in or near tumorous tissue at the treatment site in the patient so that the tumorous tissue is exposed to the palladium-103.
Dependencies are inferred from the claim text.