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US 6,464,680 B1Granted
Ultrasonic enhancement of drug injection
AssigneePharmasonics, Inc.
InventorsAxel Brisken, Robert Zuk, John McKenzie, Jeff Isner, Meno Nassi
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Abstract
A method of enhancing cellular absorption of a substance delivered into a target region of a patient's body, comprising: (a) delivering the substance to the target region; and (b) directing vibrational energy to the target region, wherein the vibrational energy is of a type and in an amount sufficient to enhance absorption into cells of the target region.
Claims21
A method of enhancing cellular absorption of a substance delivered into a target region of a patient's body, comprising:
- (a) injecting the substance into solid tissue in the target region;
- and
- (b) directing vibrational energy to the target region, said vibrational energy having a Mechanical Index in the range of 0.3 to 15 and having a Thermal Index of less than 4.0, said vibrational energy being of a type and in an amount sufficient to enhance absorption into cells of the target region.
Dependencies are inferred from the claim text.