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US 6,463,317 B1Granted
Device and method for the endovascular treatment of aneurysms
AssigneeRegents of the University of Minnesota
InventorsJohn Kucharczyk, Richard Latchaw
Life of this patent
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AssigneeRegents of the University of Minnesota
InventorsJohn Kucharczyk, Richard Latchaw
Estimating the term…
This invention provides a method and a device for treating hemodynamically significant aneurysms especially in the intracranial and extracranial circulation regions using either X-ray fluoroscopy or real-time magnetic resonance (MR) imaging guidance. An MR-visible parachute-shaped occlusion device, e.g., containing multiple elongated filamentary loops made of a memory metal, elastomeric hydrogel or other expansile material, is deployed into the aneurysm by radial expansion of the expansile material outwardly into contact with the interior aneurysm surface. The device is firmly positioned against the interior aneurysm surface using a coating which adheres to that interior aneurysm surface. The device may be filled with a hardenable polymer for permanent and complete aneurysm occlusion. Wide-neck aneurysms may be treated with the same device, with the addition of a temporary balloon expanded in the parent vessel to allow expansion of the occluding device within the aneurysm, instillation of the polymer into the device, and detachment of the device from the transporting catheter. Detachment of the aneurysm occlusion device from a transport catheter is achieved by mechanical, electrical and/or chemical decoupling. A coating applied to the surface of the parachute device may induce thrombotic occlusion of the aneurysm by timed delivery of biologic modifier drugs which promote collagen formation, fibroblast growth, and endothelial ingrowth within the aneurysm. The catheter systems may have attached microcoils or may be impregnated with MR-visible agents to permit visualization in MR imaging systems.
An image guidance system for the treatment or thrombotic occlusion of aneurysms in the human cerebrovascular system under either x-ray fluoroscopy or magnetic resonance imaging guidance, said system comprising:
A process for the treatment of aneurysms in the human cerebrovascular system under magnetic resonance imaging or X-ray fluoroscopy, said process comprising the steps of:
A process for treatment of a wide-neck aneurysm with imaging to monitor progress of delivery of a microcatheter device to a site of an aneurysm by x-ray fluoroscopy or magnetic resonance imaging, the process comprising:
Dependencies are inferred from the claim text.