Dihydrodipicolinate synthase from Bacillus methanolicus
AssigneeAjinomoto Co., Inc.
InventorsNobuharu Tsujimoto, Hisashi Yasueda, Yoshio Kawahara, Shinichi Sugimoto
Life of this patent
Estimating the term…
Abstract
The present invention provides dihydropicolinate synthase and dihydrodipicolinate reductase enzymes from Bacillus methanolicus, polynucleotides encoding the enzymes, and methods of producing L-lysinse in microorganisms expressing the enzymes.
Claims4
An isolated protein comprising a substitution, deletion, insertion or addition of not more than 50 amino acids in SEQ ID NO:2, which has dihydrodipicolinate synthase activity.
An isolated protein which is encoded by a DNA that hybridizes under stringent conditions to nucleotides 1 to 924 of SEQ ID NO:1, wherein said stringent conditions comprise washing in 1×SSC and 0.1% SDS at 60° C. wherein said protein has dihydrodipicolinate synthase activity.
An isolated protein comprising the amino acid sequence of SEQ ID NO:2.
Dependencies are inferred from the claim text.