US 6,461,586 B1Granted

Method of magnetic resonance focused surgical and therapeutic ultrasound

AssigneeImarx Therapeutics, Inc.

InventorEvan C. Unger

Life of this patent

Estimating the term…

Abstract

A novel method for the controlled delivery of therapeutic compounds to a region of a patient, using magnetic resonance focused therapeutic ultrasound, is disclosed.

Claims51

Dependent claims

A method for the controlled delivery of therapeutic compounds to a region of a patient using magnetic resonance focused therapeutic ultrasound comprising:

administering a contrast medium for magnetic resonance imaging comprising gas filled vesicles which comprise a therapeutic compound to a patient;
scanning said patient with magnetic resonance imaging using said contrast medium to determine the presence of the vesicles in the region;
and
applying ultrasound to said region to rupture said vesicles to release the therapeutic compound in the region.

1 more element

Dependencies are inferred from the claim text.

Facts

Application: 09/613,210Filed 10 Jul 2000 · division
Priority: 22 Dec 1989
Granted: 8 Oct 2002
Term ends: Not estimatedThe source records don’t support an estimate.

Classification26 codes

G01R 33/5601
Image enhancement or correction, e.g. subtraction or averaging techniques , e.g. improvement of signal-to-noise ratio and resolution: involving…
A61K 9/127
Dispersions; Emulsions: synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
A61K 9/1277
Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant: preparation processes;…
A61K 9/1278
Preparation processes; Proliposomes: post-loading, e.g. by ion or pH gradient

Family

Application07/455,707Parent of this continuation-in-part · filed 22 Dec 1989
Application07/569,828Parent of this continuation-in-part · filed 20 Aug 1990
Application07/716,899Parent of this continuation-in-part · filed 18 Jun 1991
Application07/717,084Parent of this continuation-in-part · filed 18 Jun 1991
Application08/076,239Parent of this continuation-in-part · filed 11 Jun 1993
Application08/076,250Parent of this continuation-in-part · filed 11 Jun 1993
Application08/159,687Parent of this continuation-in-part · filed 30 Nov 1993
Application08/160,232Parent of this continuation-in-part · filed 30 Nov 1993
Application08/212,553Parent of this continuation-in-part · filed 11 Mar 1994
Application08/307,305Parent of this continuation-in-part · filed 16 Sep 1994
Application08/401,974Parent of this continuation-in-part · filed 9 Mar 1995
Application08/476,317Parent of this division · filed 7 Jun 1995
US 6,088,613 AParent of this division
Application08/476,317Parent of this continuation-in-part
US 5,773,024 AParent of this continuation-in-part
US 5,585,112 AParent of this continuation-in-part
US 5,469,854 AParent of this continuation-in-part
US 5,542,935 AParent of this continuation-in-part
US 5,580,575 AParent of this continuation-in-part
US 5,922,304 AParent of this continuation-in-part
US 5,228,446 AParent of this continuation-in-part
US 5,088,499 AParent of this continuation-in-part
US 6,461,586 B1This patent

From the US filing history. Foreign family members aren’t listed.

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Abstract

A novel method for the controlled delivery of therapeutic compounds to a region of a patient, using magnetic resonance focused therapeutic ultrasound, is disclosed.

Facts

Application

09/613,210Filed 10 Jul 2000 · division

Priority

22 Dec 1989

Granted

8 Oct 2002

Term ends

Not estimatedThe source records don’t support an estimate.

Classification26 codes

G01R 33/5601
Image enhancement or correction, e.g. subtraction or averaging techniques , e.g. improvement of signal-to-noise ratio and resolution: involving…
A61K 9/127
Dispersions; Emulsions: synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
A61K 9/1277
Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant: preparation processes;…
A61K 9/1278
Preparation processes; Proliposomes: post-loading, e.g. by ion or pH gradient

Family

Application07/455,707Parent of this continuation-in-part · filed 22 Dec 1989

Application07/569,828Parent of this continuation-in-part · filed 20 Aug 1990

Application07/716,899Parent of this continuation-in-part · filed 18 Jun 1991

Application07/717,084Parent of this continuation-in-part · filed 18 Jun 1991

Application08/076,239Parent of this continuation-in-part · filed 11 Jun 1993

Application08/076,250Parent of this continuation-in-part · filed 11 Jun 1993

Application08/159,687Parent of this continuation-in-part · filed 30 Nov 1993

Application08/160,232Parent of this continuation-in-part · filed 30 Nov 1993

Application08/212,553Parent of this continuation-in-part · filed 11 Mar 1994

Application08/307,305Parent of this continuation-in-part · filed 16 Sep 1994

Application08/401,974Parent of this continuation-in-part · filed 9 Mar 1995

Application08/476,317Parent of this division · filed 7 Jun 1995

US 6,088,613 AParent of this division

Application08/476,317Parent of this continuation-in-part

US 5,773,024 AParent of this continuation-in-part

US 5,585,112 AParent of this continuation-in-part

US 5,469,854 AParent of this continuation-in-part

US 5,542,935 AParent of this continuation-in-part

US 5,580,575 AParent of this continuation-in-part

US 5,922,304 AParent of this continuation-in-part

US 5,228,446 AParent of this continuation-in-part

US 5,088,499 AParent of this continuation-in-part

US 6,461,586 B1This patent

From the US filing history. Foreign family members aren’t listed.