Modified factor VIII
AssigneeEmory University
InventorJohn S. Lollar
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Abstract
The invention relates to a modified B-domainless form of porcine factor VIII, to a DNA encoding the same, and to the use thereof for treatment of hemophilia.
Claims10
An isolated DNA molecule encoding the amino acid sequence of POL1212 as set forth in SEQ ID NO:38.
An isolated mammalian host cell containing and replicating an expression vector comprising DNA encoding the amino acid sequence of POL1212 as set forth in SEQ ID NO:38.
A method for producing a modified porcine factor VIII protein having the amino acid sequence of SEQ ID NO:38 comprising expressing in a mammalian host cell a DNA molecule encoding the amino acid sequence of SEQ ID NO:38.
Dependencies are inferred from the claim text.