Microfluidic devices and methods
AssigneeZyomyx, Inc.
InventorsPaul Jedrzejewski, Steffen Nock, Peter Wagner, Pierre Indermuhle, Frank G. Zaugg
Life of this patent
Estimating the term…
Abstract
Embodiments of the invention are directed to microfluidic devices. In one embodiment, a microanalysis chip comprises a body having at least one transfer-separation channel with a channel bottom that has a bottom opening. The transfer-separation channel terminates in a discharge aperture.
Claims31
A microanalysis chip comprising a body defining at least one transfer-separation channel including a channel bottom having a bottom opening, the transfer-separation channel terminating in a discharge aperture, wherein the bottom opening forms a well.
A microanalysis chip comprising a body defining at least one transfer-separation channel including a channel bottom having a bottom opening, the transfer-separation channel terminating in a discharge aperture, wherein the bottom opening is cooperatively structured to receive a pillar of a sample chip.
A microfluidic assembly comprising:
- a microfluidic chip comprising (i) a body having a bottom surface, (ii) a plurality of discharge apertures, and (iii) a plurality of transfer-separation channels in the body, each transfer-separation channel defined by a channel bottom with a bottom opening, and having a portion upstream of the bottom opening and a portion downstream of bottom opening, and wherein each transfer-separation channel terminates at one of the discharge apertures;
- and
- a sample chip comprising a base including a non-sample surface and a plurality of sample structures, each sample structure including a sample surface, wherein the sample surfaces are elevated with respect to the non-sample surface.
A microfluidic assembly comprising:
- a microfluidic chip comprising (i) a body having a bottom surface, (ii) a plurality of discharge apertures, and (iii) a plurality of transfer-separation channels in the body, each transfer-separation channel defined by a channel bottom with a bottom opening, and having a portion upstream of the bottom opening and a portion downstream of bottom opening, and wherein each transfer-separation channel terminates at one of the discharge apertures;
- and
- a sample chip comprising a base including a non-sample surface and a plurality of sample structures, each sample structure including a sample surface, and wherein each sample structure comprises a pillar, wherein the sample surface is on the pillar.
A microfluidic assembly comprising:
- a microfluidic chip comprising (i) a body having a bottom surface, (ii) a plurality of discharge apertures, and (iii) a plurality of transfer-separation channels in the body, each transfer-separation channel defined by a channel bottom with a bottom opening, and having a portion upstream of the bottom opening and a portion downstream of bottom opening, and wherein each transfer-separation channel terminates at one of the discharge apertures;
- a sample chip comprising a base including a non-sample surface and a plurality of sample structures, each sample structure including a sample surface, and
- a seal between the microfluidic chip and the sample chip.
A system for analyzing analytes, the system comprising:
- an analysis assembly comprising (i) a microanalysis chip comprising a body comprising at least one transfer-separation channel defined by a channel bottom having a bottom opening, the transfer-separation channel terminating in a discharge aperture, and (ii) a sample chip having a plurality of sample surfaces, wherein the sample surfaces are on pillars;
- and
- an analysis device adapted to receive an analyte from the discharge aperture.
Dependencies are inferred from the claim text.