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US 6,448,083 B1Granted
Receptor-mediated gene delivery using bacteriophage vectors
AssigneeSelective Genetics, Inc.
InventorsDavid Larocca, Andrew Baird, Wendy Johnson
Life of this patent
Estimating the term…
Abstract
Filamentous phage particles displaying a ligand on their surface are used to deliver a therapeutic gene to a cell. The ligand is a fusion protein with a phage capsid protein, covalently conjugated to phage particles, or complexed with modified phage particles.
Claims22
A method of gene delivery to cultured cells, comprising:
- contacting a mammalian cell with filamentous phage particles presenting a ligand on their surfaces, wherein a vector within the phage encodes a gene product under control of a promoter.
Dependencies are inferred from the claim text.