Antisense modulation of p38 mitogen activated protein kinase expression
AssigneeIsis Pharmaceuticals, Inc.
InventorsBrett P. Monia, William A. Gaarde, Pamela Nero, Robert McKay
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Abstract
Compositions and methods for the treatment and diagnosis of diseases or conditions amenable to treatment through modulation of expression of a gene encoding a p38 mitogen-activated protein kinase (p38 MAPK) are provided. Methods for the treatment and diagnosis of diseases or conditions associated with aberrant expression of one or more p38 MAPKs are also provided.
Claims13
An antisense compound 8 to 30 nucleobases in length targeted to a nucleic acid molecule encoding p38 mitogen activated protein kinase, wherein said antisense compound inhibits the expression of said p38 mitogen activated protein kinase and comprises SEQ ID NO:
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