Composite materials and adhesion promoters for dental applications
AssigneeBioMat Sciences, Inc.
InventorsIvan Stangel, Thomas Ellis, Erik Kruus, Edward Sacher, Robin Drew, Jingwei Xu
Life of this patent
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Abstract
Composite materials particularly suitable in the dental art as a tooth filling material including a polymer matrix, a metal, metal alloy, metal oxide particulate, or combinations thereof, in the presence or absence of colloidal silica, and a coupling agent to adhere the particulate to the polymer matrix. Adhesion can also be facilitated by cleaning and/or coating the particulates prior to incorporation into the polymer matrix. One or two paste systems of the composition with suitable initiators, accelerators, etc. can be formulated.
Claims19
A composition comprising a polymerizable material in an amount of from about 1 to about 79 pecent by weight of the composition, filler particles in an amount of from about 20 to about 98 percent by weight of the composition, said filler particles having a metal surface that is capable of forming a bond with at least one of a thiol or a phosphate, wherein the metal is selected from groups VIIB, VIII, IB, and IVA of the periodic table of the elements or their oxides;
- and a coupling agent including a functionality capable of forming a bond with the metal, and said coupling agent comprising at least one of a thiol-containing compound or a polymerizable phosphate.
A composite comprising a filler having a coating of a metal and an omega-terminated thiol or disulfide having the formulae:
- HS—R2—(Z)n or (Z)n—R2—S—S—R2—(Z)n
- where HS is the thiol, R2 is the linkage between the thiol and omega termination being comprised of (CH2)m, m is an integer from 2 to 20, n is an integer from 1 to 20, and Z is the reactive omega termination having at least one unsaturated group.
A composition comprising a polymerizable material in an amount of from about 1 to about 79 percent by weight of the composition, filler particles present in mount of a from about 20 to 98 percent by weight, said filler particles having a surface which is capable of forming a bond with sulphur, and a thiol coupling agent in an effective amount.
A method of preparing a composite comprising:
- coupling a surface of a filler having a coating of a metal to a coupling agent having the formulae:
- where HS is the thiol, R2 is the linkage between the thiol and omega termination being comprised of (CH2)m, m is an integer from 2 to 20, i is an integer from 1 to 20, Z is the reactive omega termination having at least one unsaturated group, R1 is a hydrogen atom, alkyl C1-C4, or CN, R is an aliphatic, cycloaliphatic or aryl radical containing from 1 to 10 carbon atoms and having a valence of n+1, and n is an integer from 1 to 5.
A method of filling a tooth comprising
- applying a composition to a surface of a tooth, the composition including a polymerizable material in an amount of from about 1 to about 79 percent by weight of the composition, filler particles in an amount of from about 20 to about 98 percent by weight of the composition, said filler particles having a metal surface that is capable of forming a bond with at least one of a thiol or a phosphate ester, wherein said metal is selected from groups VIIB, VIII, IB, IIB, and IVA of the periodic table of the elements or their oxides;
- and
- a coupling agent including a functionality capable of forming a bond with the surface, said coupling agent being provided on said filler particles, and the coupling agent comprising at least one of a thiol-containing compound or a polymerizable phosphate;
- and
- curing the composition.
Dependencies are inferred from the claim text.