Product and method to reduce stress induced immune suppression
AssigneeAbbott Laboratories
InventorsStephen J. DeMichele, John W. McEwen, Steven M. Wood
Life of this patent
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Abstract
In its broadest aspect, the present invention is directed to the discovery of immunonutritional products that are useful in reducing the immunological system suppression that results from stress. The stress may be in the form of physical exertion, mental exhaustion, disease states and the like. In one embodiment, the invention relates to a nutritional composition comprising a structured glyceride component and an antioxidant system. This nutritional composition has been shown to be highly effective in reducing immune system down regulation or dysregulation as a result of stress.
Claims28
A liquid nutritional composition suitable for oral consumption comprising, on a per liter basis:
- a) from 1 to 10 grams of vitamin C,
- b) from 400 to 2000 international units of vitamin E;
- c) from 15 to 100 milligrams of beta-carotene;
- d) from 100 to 800 micrograms of selenium, and;
- e) from 2 to 200 grams of a structured glyceride component, characterized in that it contains about 50% by weight or more of triglyceride species and at least 40% of said triglyceride species have the following three characteristics:
- (i) about 33 to 70 wt. % of acyl moieties having 4 to 12 carbon atoms;
- (ii) about 30 to 67 wt. % of acyl moieties having more than 12 carbon atoms, and;
- (iii) an equivalent carbon number of greater than 30 to less than 48.
A pharmaceutical composition suitable for oral administration comprising:
- a) from 0.5 to 5.0 grams of vitamin C;
- b) from 200 to 1000 international units of vitamin E;
- c) from 7.5 to 50 mg of beta-carotene;
- d) from 50 to 400 micrograms of selenium, and;
- e) from 10 to 100 grams of a structured glyceride component, characterized in that it contains about 50% by weight or more of triglyceride species and at least 40% of said triglyceride species having the following three characteristics:
- (i) about 33 to 70 wt. % of acyl moieties having 4 to 12 carbon atoms;
- (ii) about 30 to 67 wt. % of acyl moieties having more than 12 carbon atoms, and;
- (iii) an equivalent carbon number of greater than 30 to less than 48.
Dependencies are inferred from the claim text.