Lavendamycin analogs, quinoline-5,8-diones and methods of using them

A compound having the following formula:

• wherein,
• R1 is H, a halogen atom, NO2, CN, OR13, SR13, N(R13)2,
• an alkyl, aryl, cycloalkyl, alkenyl, alkynyl, or heteroalkyl, heterocyclic, heteroalkenyl or heteroalkynyl residue, each of which may be substituted or unsubstituted, with the proviso that when x is NH2, R1 is not OR13, alkyl or heteroalkyl,
• R2 is H,
• R3 is H or CH3,
• R10 and R13, which may be the same or different, each is independently H or an alkyl, cycloalkyl, alkenyl, alkynyl, aryl or heterocyclic residue, each of which may be substituted or unsubstituted, and
• Z is CH3, and
• pharmaceutically acceptable salts thereof.