Neurogenic differentiation gene neurod3 and methods for inducing differentiation of cells
AssigneeFred Hutchinson Cancer Research Center
InventorStephen J. Tapscott
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Abstract
Provided are methods of classifying and prognosticating human neuroectodermal tumors by analyzing a sample of the tumor to determine whether various bHLH proteins are detectably expressed in the sample. In the methods disclosed herein, expression of the bHLH genes is assessed by measuring transcripts or proteins expressed from the genes.
Claims6
An isolated nucleic acid molecule which hybridizes under stringent conditions with a nucleic acid molecule having the sequence of SEQ ID No:12, and which encodes a functionally active neuroD3 polypeptide.
An isolated nucleic acid molecule, wherein the nucleic acid molecule encodes a polypeptide having the amino acid sequence of SEQ ID No.:13.
Dependencies are inferred from the claim text.