Reversibly, non-covalent bound surface coating
AssigneeForskarpatent I Syd AB
InventorsThomas Arnebrant, Börje Sellergren, Aleksander Swietlow
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Abstract
A surface coating and its use in chemical analysis, electronics, and optoelectronics is disclosed. The surface coating is characterized in that it comprises an amphiphile reversibly bound to a substrate by non-covalent interaction, preferably by polar interaction. The amphiphile is a bolaamphiphile, such as pentamidine.
Claims15
A surface coating comprising a self-assemble layer of bola amphiphilic amidine molecules reversibly bound to a substrate by cyclic ion pairs formed by polar interaction between the amidine groups of the bola amphiphilic amidine molecules and anionic groups of the substrate.
A method for preparing a surface coating, comprising
- providing a substrate with anionic groups;
- providing bola amphiphilic amidine molecules;
- providing a self-assembled layer of the bola amphiphilic amidine molecules on the substrate by
- reversibly binding the bola amphiphilic amidine molecules to the substrate by cyclic ion pairs formed by polar interaction between the amidine groups of the bola amphiphilic amidine molecules and the anionic groups of the substrate, such that the bola amphiphilic amidine molecules coat the surface of the substrate.
A biosensor having a substrate with a coating comprising a self-assembled layer of amphiphilic amidine molecules, said amphiphilic amidine molecules having a polar amidine group linked by a non-polar group to a functional group and being reversibly bound to the substrate by cyclic ion pairs formed by polar interaction between the amidine groups of the amphiphilic amidine molecule and anionic groups of the substrate.
Dependencies are inferred from the claim text.