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US 6,444,224 B1Granted
Intra-vaginal device for pigs
AssigneeInterag
InventorsMichael John Rathbone, Shane Burccraff, James Frederick Pharaoh
Life of this patent
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AssigneeInterag
InventorsMichael John Rathbone, Shane Burccraff, James Frederick Pharaoh
Estimating the term…
Disclosed herein is a porcine intra-vaginal device of a shape and size adapted to be positionable in the vaginal tract across the hymenal ring of a target animal (e.g., a gilt) to extend to both sides of the hymenal ring of the animal. The device once inserted delivers progesterone from a progesterone impreganated matrix on either side of the hymenal ring, the progesterone releasing surface being at least 150 cm2 in total area. Variable geometry means (preferably for vestibular engagement) ensure retention of the devices (e.g., for at least 7 to 14 days) where, in the preferred device, the progesterone load of from 1.9 to 2.5 g within 1.2 mm of the release surface can, by maintaining a progesterone blood plasma level (equating to a progestrone blood plasma level in excess of 4 ng/mL measured in an ovariectomised animal), ensure or prompt the onset of oestrus within 3 to 5 days after device removal.
A porcine intra-vaginal device having a shape and a size that extends to both sides of the hymenal ring of the female pig, wherein the device comprises a matrix or matrices having a progesterone load of at least 1.9 g and is at least 150 cm3 in total area.
A porcine intra-vaginal device having a shape and a size that extends to both sides of the hymenal ring of the female pig, wherein the device comprises a progesterone impregnated matrix or matrices and a variable geometry means which deploy in the vestibule upon insertion to retain the device in the vaginal tract.
The device of claim wherein the device has a spine with a progesterone impregnated silicone rubber matrix formed thereabout.
An intra-vaginal device having a shape and size that extends to both sides of the hymenal ring of a female pig comprising
A device of claim wherein said wing members lie in the same plane.
An intra-vaginal device for delivering a substance into a female pig having a shape and size that extends to both sides of the hymenal ring of the female pig comprising
An intra-vaginal device for delivering a substance into a pig comprising
Dependencies are inferred from the claim text.