Reinforced matrices
AssigneeVerigen Transplantation Services International AG
InventorsSamuel Asculai, Bruno Giannetti
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Abstract
A reinforced matrix membrane containing one or more scaffold-forming proteins suitable for cell growth and for use in chondrocyte cell transplantation, and method of making same. The scaffold is incubated with the collagen matrix in solutions, colloidal dispersions, or suspensions of stabilizing proteins. The reinforced matrix may be used in tissue engineering, cartilage transplantation, bone and cartilage grafting, healing, joint repair and the prevention of arthritic pathologies.
Claims19
A method for making a reinforced matrix comprising
- incubating collagen with a scaffold-forming protein to form a mixture;
- lyophilizing the mixture to form a fleece material;
- and
- pressing the fleece material into sheets to form the matrix.
A reinforced fleece membrane comprising a collagen matrix and a scaffold-forming protein.
A composition for implantation or for arthroscopic surgery comprised of chondrocytes and a fleece membrane comprising a collagen matrix and a scaffold-forming protein.
Dependencies are inferred from the claim text.