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US 6,444,200 B1Granted
Composition and method for dermal and transdermal administration of a cytokine
AssigneePharmaDerm Laboratories Ltd.
InventorsMarianna Foldvari, Sam Kwadwo Attah-Poku
Life of this patent
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Abstract
A composition for transdermal administration of a cytokine is described. The composition includes a conjugate composed of a cytokine, such as an interferon, and at least one fatty acid moiety covalently attached to the cytokine. The conjugate has enhanced cutaneous delivery relative to the cytokine alone.
Claims5
A pharmaceutical composition for dermal or transdermal administration of a cytokine, comprising
- a conjugate composed of a cytokine and at least one unsaturated fatty acid moiety having between 16 -20 carbon atoms covalently attached to the cytokine, said conjugate having a substantially higher rate if skin penetration than the cytokine alone.
Dependencies are inferred from the claim text.