Electromagnetic cardiac biostimulation
AssigneeBiosense, Inc.
InventorsUri Oron, Avraham Matcovitch
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Abstract
Methods and apparatus for biostimulation of a myocardial tissue, by irradiating the myocardial tissue with a source of electromagnetic radiation which causes biostimulation of the myocardial tissue. Preferably, the electromagnetic radiation is selected from the group consisting of infrared, visible light and ultraviolet radiation. Typically, the tissue is irradiated after the myocardial tissue develops an infarct of a given size, such that irradiating the myocardial tissue causes a reduction in the size of the infarct. The irradiation may also cause regeneration of cardiomyocytes in the infarct and help to preserve structure and activity of mitochondria in cardiomyocytes in the infarct.
Claims37
A method for biostimulation of a myocardial tissue of a heart, said method comprising:
- introducing a catheter having at least one position sensor into said heart;
- tracking the location of said catheter within said heart using at least one position sensor;
- positioning said catheter at said myocardial tissue of said heart;
- irradiating said myocardial tissue without creating a channel in said myocardial tissue via a waveguide introduced by said catheter into said heart with a source of electromagnetic radiation having a power output in the range of 5 mW to 5 W and a wavelength in the range of 250 nm to 940 nm;
- and
- inducing cells in said myocardial tissue to synthesize newly-formed contractile proteins as a result of said irradiation.
A method for biostimulation of a myocardial tissue of a heart, said method comprising:
- introducing a catheter into said heart;
- positioning said catheter at said myocardial tissue of said heart;
- receiving physiological signals from said myocardial tissue with said catheter;
- irradiating said myocardial tissue without creating a channel in said myocardial tissue via a waveguide introduced by said catheter into said heart with a source of electromagnetic radiation having a power output in the range of 5 mW to 5 W and a wavelength in the range of 250 nm to 940 nm in response to the signals received therefrom;
- and
- inducing cells in said myocardial tissue to synthesize newly-formed contractile proteins as a result of said irradiation.
Dependencies are inferred from the claim text.