Medicament respiratory delivery device

A medicament respiratory delivery device, comprising:

• a housing comprised of opposed thermoformed thermoplastic bonded sheets, said sheets having formed therebetween a chamber, an inlet communicating with said chamber, a collapsible pressure actuator having an outlet communicating with said inlet of said chamber and an outlet communicating with said chamber opposite said inlet of said chamber;
• a medicament cartridge in said chamber having a body encapsulated by said sheets, said body having opposed first and second ends, a passage extending through said body through said opposed first and second ends, a pierceable closure sealing said passage at said first end opposite said inlet of said chamber, and a burstable membrane sealing said passage at said second end of said body opposite said outlet of said chamber;
• and
• a piercing element having a piercing end adjacent said pierceable closure movable relative to said body of said cartridge to pierce said pierceable closure upon actuation of said collapsible pressure actuator delivering fluid under pressure to said passage of said cartridge, thereby rupturing said burstable membrane and expressing medicament in said passage entrained in fluid to said outlet.

A medicament respiratory delivery device, comprising:

• a housing formed of two opposed thermoformed thermoplastic bonded sheets, said sheets having formed therebetween a chamber, an inlet communicating with said chamber, a bulb-shaped collapsible pressure actuator having an outlet communicating with said inlet of said chamber, and an outlet communicating with said chamber opposite said inlet of said chamber;
• a medicament cartridge in said chamber having a body encapsulated between said opposed thermoformed thermoplastic bonded sheets, said body having opposed first and second ends, a passage extending through said body through said first and second ends, a pierceable closure sealing said passage at said first end of said body opposite said inlet of said chamber, and a burstable membrane sealing said passage at said second end opposite said outlet of said chamber;
• and
• a piercing element having an actuator portion located within said bulb-shaped collapsible pressure actuator and a shaft connected to said actuator portion having a distal piercing end adjacent said pierceable closure of said cartridge, whereby collapse of said bulb-shaped collapsible pressure actuator engages said actuator portion of said piercing element to extend said shaft, piercing said pierceable closure and delivering fluid under pressure to said passage of said cartridge, rupturing said burstable membrane and delivering medicament to said outlet communicating with said chamber.