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US 6,441,271 B1Granted
Plant histidine biosynthetic enzymes
AssigneeE. I. Du Pont de Nemours and Company
InventorsStephen M. Allen, William D. Hitz
Life of this patent
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Abstract
This invention relates to an isolated nucleic acid fragment encoding a histidine biosynthetic enzyme, imidazoleglycerol-phosphate dehydratase. The invention also relates to the construction of a chimeric gene encoding all or a portion of the histidine biosynthetic enzyme, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the histidine biosynthetic enzyme in a transformed host cell.
Claims10
An isolated polynucleotide comprising:
- (a) a nucleotide sequence encoding a polypeptide having imidazoleglycerol-phosphate dehydratase activity, wherein the amino acid sequence of the polypeptide and the amino acid sequence of SEQ ID NO:2 have at least 96% sequence identity based on the Clustal alignment method, or
- (b) the complement of the nucleotide sequence, wherein the complement contains the same number of nucleotides as the nucleotide sequence, and the complement and the nucleotide sequence are 100% complementary.
Dependencies are inferred from the claim text.