US 6,441,167 B1Granted

Cinoxacin lanthanide chelates and their use as biomolecular probes

AssigneeSmithKline Beecham Corporation

InventorsColin Andrew Leach, Keith James Millan Moore, Steven James Stanway

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Abstract

This invention relates to novel compounds that can complex with lanthanide cations, processes for their preparation and the use of the resulting lanthanide chelates as biomolecular probes.

Claims5

Dependent claims

A lanthanide chelate comprising one or more sensitiser groups covalently attached to a lanthanide chelating group, wherein the sensitiser group is of formula (I)

where X is a group that couples the said sensitiser group to the said chelating group.

Dependencies are inferred from the claim text.

Facts

Application: 09/720,172Filed 16 Feb 2001
Priority: GB 981377625 Jun 1998
Granted: 27 Aug 2002
Term ends: Not estimatedThe source records don’t support an estimate.

Classification8 codes

C07D 491/04
In which the condensed system contains two hetero rings: ortho-condensed systems
C07C 229/16
The nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic…
C07C 229/76
Compounds containing amino and carboxyl groups bound to the same carbon skeleton: metal complexes of amino carboxylic acids
C07C 233/83
With the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom: of an acyclic saturated…

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