Antitumor compositions containing taxane derivatives
AssigneeAventis Pharma S.A.
InventorMarie-Christine Bissery
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Abstract
A pharmaceutical composition comprised of acetocyclopropyl taxotere or a derivatve thereof, and at least one of an alkylating agent, an antimetabolite, a spindle poison, an epidophyllotoxin, an antibiotic, an enzyme, a topoisomerase inhibitor, a platinum coordination complex, a biological response modifier or a growth factor inhibitor is described.
Claims19
A pharmaceutical composition comprised of the compound of formula 1:
- or a derivatve thereof, and at least one of an alkylating agent, an antimetabolite, a spindle poison, an epidophyllotoxin, an antibiotic, an enzyme, a topoisomerase inhibitor, a platinum coordination complex, a biological response modifier or a growth factor inhibitor.
A pharmaceutical composition having therapeutic synergy in the treatment of neoplastic disease comprising a compound of the formula:
- and doxorubicin.
A pharmaceutical composition having therapeutic synergy in the treatment of neoplastic disease comprising a compound of the formula:
- and navelbine.
A pharmaceutical composition having therapeutic synergy in the treatment of neoplastic disease comprising a compound of the formula:
- and cisplatin.
A pharmaceutical composition having therapeutic synergy in the treatment of neoplastic disease comprising a compound of the formula:
- and CPT 11.
Dependencies are inferred from the claim text.