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US 6,440,978 B2Granted
Therapeutic agent for dermatitis
AssigneeNippon Zoki Pharmaceutical Co., Ltd.
InventorsHaruo Yoshii, Akihiro Fujita
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AssigneeNippon Zoki Pharmaceutical Co., Ltd.
InventorsHaruo Yoshii, Akihiro Fujita
Estimating the term…
The present invention provides a therapeutic agent for dermatitis, particularly a therapeutic agent for atopic dermatitis, which is very safe and which shows few adverse side-effects in comparison to, for example, steroidal agents. The present invention relates to a therapeutic agent containing a compound represented by the following formula (I) or a pharmaceutically acceptable salt or hydrate thereof as an effective ingredient: wherein R is hydrogen or a halogen. The therapeutic agent for dermatitis according to the present invention effectively and in a dose-dependent manner suppresses antigen-induced swelling in a mouse ear, a recognized animal model for atopic dermatitis, and suppresses the antigen-induced flare-up reaction in mice which occurred with the swelling reaction. In addition, no adverse reaction in the skin are observed.
A method for the treatment of dermatitis comprising administering to a patient in need of such treatment a pharmaceutically effective amount of at least one compound represented by the following formula (I) or a pharmaceutically acceptable salt or hydrate thereof:
Dependencies are inferred from the claim text.