Heterocyclic compounds useful as oxido-squalene cyclase inhibitors

A compound of formula I, or a pharmaceutically acceptable salt thereof

• wherein:
• R is selected from halogeno, cyano, nitro, carboxy, (1-6C)alkyl, (1-6C)alkoxy, (1-6C)alkanoyl, (1-6C)alkoxycarbonyl and halogeno(1-6C)alkyl;
• R1 is selected from hydrogen, amino, halogeno, cyano, nitro, carboxy, (1-6C)alkyl, (1-6C)alkoxy, (1-6C)alkanoyl, (1-6C)alkoxycarbonyl, halogeno(1-6C)alkyl, N-(1-6C)alkylamino, N,N-di-[(1-6C)alkyl]amino, (1-6C)alkylthio, (1-6C)alkylsulphinyl and (1-6C)alkylsulphonyl;
• m is 1 or 2;
• A is selected from a direct bond and (1-4C)alkylene;
• T1, T2 and T3 are each N;
• wherein the heterocyclic ring containing T1 and the heterocyclic ring containing T2 may, independently, be optionally substituted by one or more substituents selected from (1-6C)alkyl, (1-6C)alkoxy, phenyl(1-4C)alkyl, halogeno and (1-6C)alkoxycarbonyl;
• and
• Q is selected from a heteroaryl moiety containing up to 3 heteroatoms selected from nitrogen, oxygen and sulphur, or from phenyl, naphthyl, phenyl(1-6C)alkyl and phenyl(2-6C)alkenyl;
• and wherein Q may be unsubstituted or may bear one or more substituents selected from halogeno, hydroxy, amino, nitro, cyano, carboxy, carbamoyl, (1-6C)alkyl, (2-6C)alkenyl, (2-6C)alkynyl, (1-6C)alkoxy, (3-6C)cycloalkyl, (3-6C)cycloalkyl(1-4C)alkyl, (1-4C)alkylenedioxy, (1-6C)alkylamino, N,N-di-[(1-6C)alkyl]amino, N-(1-6C)alkylcarbamoyl, di-N[(1-6C)alkyl]carbamoyl, (1-6C)alkanoylamino, (1-6C)alkoxycarbonyl, (1-6C)alkylthio, (1-6C)alkylsulphinyl, (1-6C)alkylsulphonyl, halogeno(1-6C)alkyl, (1-6C)alkanoyl and a heteroaryl group comprising a 5- or 6-membered monocyclic heteroaryl ring containing up to three heteroatoms selected from nitrogen, oxygen and sulphur.