Method of inducing angiogenesis in nonis chemic skeletal muscle
AssigneeInstituto Dermopatico dell'Immacolata
InventorMaurizio C. Capogrossi
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Abstract
The present invention provides a method for enhancing the level of perfusion of blood to a nonischemic skeletal muscle, e.g., by inducing angiogenesis or collateral blood formation in a nonischemic skeletal muscle at risk of being affected by ischemia or a vascular occlusion, by administration of a pharmaceutical composition comprising a DNA encoding an angiogenic peptide, such that the level of perfusion of blood to the nonischemic skeletal muscle is enhanced.
Claims18
A method for enhancing the level of perfusion of blood to a nonischemic skeletal muscle at risk of suffering from ischemic damage or at risk of being affected by a vascular occlusion comprising directly administering to a nonischemic skeletal muscle a pharmaceutical composition comprising (a) a pharmaceutically acceptable carrier and (b) a DNA encoding an angiogenic peptide, such that the level of perfusion of blood to the nonischemic skeletal muscle is enhanced.
Dependencies are inferred from the claim text.