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US 6,440,940 B1Granted
Bioresorbable alginate derivatives
OwnerPeter J. Doyle, Wilson Harvey +1inventors
InventorsPeter J. Doyle, Wilson Harvey, Reginald L. Stilwell
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Abstract
The invention provides oxidized alginates that are bioresorbable. The oxidized alginates are prepared by controlled oxidation of alginates with nitrogen tetroxide or the like, The invention also provides pharmaceutical compositions, wound dressings, surgical implants and prostheses comprising the oxidized alginate derivatives.
Claims20
An oxidized alginate which is substantially insoluble in water and bioresorbable.
A process to prepare an oxidized alginate comprising the steps of:
- contacting an alginate with an oxidizing agent;
- forming a salt of the alginate with divalent or trivalent cations;
- thereby forming an oxidized alginate which is bioresorbable and insoluble in water;
- followed by isolating and washing the oxidized alginate.
1 more element
A wound dressing comprising a pad which comprises an oxidized alginate which is bioresorbable.
Dependencies are inferred from the claim text.