Combinatorial synthesis and screening of organometallic compounds and catalysts

A method comprising:

• providing more than 3 metal-binding ligands in individual regions in solution on a substrate, wherein said metal-binding ligands are ancillary, chiral ligands and are different from each other;
• delivering a metal ion to said regions, wherein said delivered metal ion may be the same or different for each region and said metal ion is in the form of a metal precursor having the general formula LnMXm, wherein L is a neutral Lewis base, n is an integer greater than or equal to zero;
• M is a metal;
• X is an anionic ligand;
• and m is an integer greater than zero;
• and
• subjecting the contents of each region simultaneously to a catalytic reaction of interest and determining the catalytic performance of said contents relative to each other.