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US 6,440,702 B1Granted
Nucleic acids encoding modified ciliary neurotrophic factors
AssigneeRegeneron Pharmaceuticals, Inc.
InventorNikos Panayotatos
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Abstract
Modified ciliary neurotrophic factors and methods for their production and therapeutic use. Also described is a method of screening for novel therapeutic proteins by determining altered electrophoretic binding properties.
Claims6
An isolated and purified nucleic acid molecule comprising a nucleotide sequence encoding a modified human ciliary neurotrophic factor (CNTF) with a modification consisting of Gln63→Arg.
Dependencies are inferred from the claim text.