Renal cancer associated antigens and uses therefor

A method for determining regression, progression or onset of a condition characterized by expression of abnormal levels of a protein encoded by a nucleic acid molecule that is a NA Group 1 molecule, comprising

• monitoring a sample, from a patient who has or is suspected of having the condition, for a parameter selected from the group consisting of
• (i) the protein
• (ii) a peptide derived from the protein
• (iii) an antibody which selectively binds the protein or peptide, and
• (iv) cytolytic T cells specific for a complex of the peptide derived from the protein and an MHC molecule,
• as a determination of regression, progression or onset of said condition,
• wherein the NA group 1 molecule hybridizes under stringent conditions to a nucleic acid molecule selected from the group consisting of SEQ ID NOs:
• 1, 4, 5, 7, 10, 11, and 35, wherein said stringent condition comprise hybridization at 65° C. in hybridization buffer (3.5×SSC, 0.02% Ficoll, 0.02% polyvinyl pyrrolidone, 0.02% Bovine Serum Albumin, 2.5 mM NaH2PO4(pH7), 0.5% SDS, 2 mM EDTA) and wherein SSC is 0.15M sodium chloride/0.15M sodium citrate, pH7;
• SDS is sodium dodecyl sulphate;
• and EDTA is ethylenediaminetetracetic acid.