Biocompatible metallic materials grafted with sulfonated poly(ethylene oxide) and preparation thereof
AssigneeKorea Institute of Science and Technology
InventorsYoung-Ha Kim, Ki-Dong Park, Dong-Jun Ahn, Soo-Hyun Kim, Won-Kyu Lee
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Abstract
A surface-modified medical metallic material, which comprise a metallic substrate; a thin film of gold or silver coated on the surface of said substrate; a functional sulfur compound adsorbed on said thin film; and a sulfonated poly(ethylene oxide) (PEO) derivative chemically bonded to functional groups of said sulfur compound, and a method for the preparation thereof are disclosed. It is also disclosed a stent, a cardiac valve and a catheter prepared from the surface-modified metal material.
Claims19
A surface-modified medical metallic material, which comprises:
- a metallic substrate;
- a thin film of gold or silver coated on the surface of said substrate;
- a functional sulfur compound that forms a charge transfer complex with said film, thereby being adsorbed on said film;
- and
- a sulfonated poly(ethylene oxide) (PEO) derivative chemically bonded to functional groups of said sulfur compound.
A method for the production of a surface-modified medical metallic material, which comprises the steps of:
- (a) providing a metallic substrate;
- (b) coating a thin film of gold or silver on the surface of said substrate;
- (c) applying on said film a functional sulfur compound which can form a charge transfer complex with said film, thereby be adsorbed on said film;
- and
- (d) chemically bonding a sulfonated poly(ethylene oxide) (PEO) derivative to the functional groups of said sulfur compound.
Dependencies are inferred from the claim text.